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OCR: ieved Posterior pituitary replacement is best ac DH, which using an enzyme-resistant analogue of A nay cause itself has a short duration of action and the drug intense vasoconstriction. For this reasor wice daily, desmopressin is given (10-20ug once or nstrictor intranasally), since it is devoid of vasoco las become actions at therapeutic doses. Recently, it (100 g clear that this drug is also effective orally ncy, a three times daily). In partial ADH deficie ed by reduction in urine volume can be achie the using chlorpropramide, which increases nous ADH sensitivity of the renal tubules to endog This can, however, cause hypoglycaemia warned toparticularly in the elderly, who should b eat before retiring to bed.